Peran Insulin-like Growth Factor-1 (IGF-1) terhadap Penyakit Kardiovaskular

Authors

  • Fitrianisa Faradina Zubadi Department of Biochemistry, Faculty of Medicine, The University of Mataram, Mataram, Indonesia.
  • Herpan Harahap Department of Neurology, Faculty of Medicine, The University of Mataram, Mataram, Indonesia.
  • Legis Saputri Department of Pharmacology, Faculty of Medicine, The University of Mataram, Mataram, Indonesia.
  • Arina Windri Rivarti 2Department of Physiology, Faculty of Medicine, The University of Mataram, Mataram, Indonesia

DOI:

https://doi.org/10.29303/lmj.v3i3.5379

Keywords:

IGF-1, kardiovaskular, ateroprotektif, atherosklerosis, stroke

Abstract

Insulin-like growth factor 1 (IGF-1) is a major regulator of somatic growth that mediates the effects of growth hormone (GH). IGF-1 receptors are expressed by three major cells involved in the pathogenesis of atherosclerosis, namely endothelial cells, macrophages, and smooth muscle cells. Recent in vivo studies have discussed the effects of IGF-1 on the pathogenesis of atherosclerosis. This paper will discuss the relationship and role of IGF-1 in heart and blood vessel disease.

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Published

2024-09-30

Issue

Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3

Section

Articles