Rasio Neutrofil - Limfosit sebagai Prediktor Hasil Klinis pada Pasien dengan PPOK Eksaserbasi Akut: Tinjauan Literatur

Authors

  • Devi Chandra Juvitha Fakultas Kedokteran dan Ilmu Kesehatan Universitas Mataram , Program Studi Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Mataram, Indonesia.
  • Ni Komang Ayu Swanitri Wangiyana University of Mataram image/svg+xml , Program Studi Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Mataram, Mataram, Indonesia.
  • I Gusti Agung Ayu Eka Putri Sunari Departemen Patologi Klinik, RSUD Kota Mataram, Mataram, Indonesia

DOI:

https://doi.org/10.29303/kpa54229

Keywords:

COPD, Inflammatory biomarker, outcome copd, NLR, prognostic in COPD

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a lung disease characterized by chronic respiratory symptoms that cause progressive and persistent airflow obstruction. Numerous inflammatory markers can be used to assess the inflammatory state in COPD patients. Neutrophil-to-Lymphocyte Ratio (NLR) is an inflammatory marker that is easy and practical to examine, which is included in a complete blood count (CBC). We conducted a narrative literature review using a thematic synthesis approach on 12 articles. Five articles demonstrated that the NLR is a good predictor of mortality or death in hospitalized patients with COPD. Two articles stated that a higher NLR in COPD patients increases the likelihood of requiring intensive care (ICU), while the other five articles explained that the NLR can be a good predictor of exacerbations in COPD patients.

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Published

2026-01-31