Correlation Between Blood Glucose and Hemodialysis Adequacy in Routine Hemodialysis Patients at West Nusa Tenggara General Hospital

Abstract

Progressive kidney function decline to a GFR < 15 mL/min/1.73 m² is defined as stage 5 chronic kidney disease (end stage) or end-stage renal failure. In this condition, patients require renal replacement therapy, such as hemodialysis. Effective dialysis indicates a longer life expectancy and lower mortality rates. The effectiveness of the hemodialysis process or hemodialysis adequacy is measured by the Kt/V value, which reflects the urea clearance during each hemodialysis session. Blood sugar levels before hemodialysis are one of the predictors of hemodialysis adequacy. This study used an analytic observational method on 34 samples that met the inclusion and exclusion criteria to find correlation between blood glucose and hemodialysis adequacy in routine hemodialysis patients at West Nusa Tenggara General Hospital. Data collection was carried out at the HD Unit 2 of the Provincial General Hospital of West Nusa Tenggara. In this study, the average age of the respondents was 50 years, consisting of 64.7% male and 35.3% female. The results of the correlation analysis using the Pearson test showed no significant relationship between blood glucose levels and hemodialysis adequacy, with p=0,478 and r=-0,126. However, the Fisher exact test revealed a statistically significant relationship between gender and hemodialysis adequacy, with p<0,001. In conclusion, blood glucose levels were not associated with hemodialysis adequacy, while gender showed a statistically significant association with hemodialysis adequacy.