Vasopresin and Corticosteroid use in Septic Shock : A Review

Authors

  • Baiq Auliya Cahya Putri a:1:{s:5:"en_US";s:18:"Mataram University";}
  • Silvi Sari Dewi Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Mataram, Mataram, Indonesia
  • Atika Soleha Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Mataram, Mataram, Indonesia
  • Dela Serlina Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Mataram, Mataram, Indonesia
  • Baiq Wanda Anisa Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Mataram, Mataram, Indonesia
  • Salman Elwaro Saufi Pendidikan Profesi Dokter Fakultas Kedokteran Universitas Mataram, Mataram, Indonesia
  • Indah Sapta Wardhani Bagian/ SMF Ilmu Kesehatan Penyakit Dalam RSUD Provinsi Nusa Tenggara Barat, Mataram, Indonesia
  • Philip Habib Bagian/ SMF Ilmu Kesehatan Penyakit Dalam RSUD Provinsi Nusa Tenggara Barat, Mataram, Indonesia

DOI:

https://doi.org/10.29303/jk.v13i4.5159

Keywords:

Shock, sepsis, sepsis shock, vasopressin, corticosteroid, hydrocortisone

Abstract

Septic shock is a life-threatening organ dysfunction accompanied by abnormalities in the circulatory, cellular and metabolic systems, thereby increasing the risk of death due to the body's response to an infection. Sepsis remains a global health and economic problem. The condition of sepsis is caused by increased capillary permeability and decreased peripheral vascular resistance so it is classified as distributive shock. The main treatment for this condition is fluid resuscitation accompanied by administration of inotropic agents (vasopressors), administration of antibiotics and reducing excessive inflammation in the body. Several new studies regarding the efficacy of vasopressin therapy with corticosteroids are also being considered. Therefore, this study will discuss septic shock and its management, especially with a combination of vasopressin and corticosteroids.

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Published

2024-12-31

Issue

Vol. 13 No. 4 (2024): Jurnal Kedokteran

Section

Articles

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