Vitamin D and Type 2 Diabetes Mellitus: Role in Insulin Resistance, Glycemic Control and Long Term Complications

Indah Sapta Wardani; Aliza Raudatin Sahly; Indah Eva  Ajmala; Dewi Suryani

doi:10.29303/jk.v11i2.4689

Indah Sapta Wardani Fakultas Kedokteran, Universitas Mataram
Aliza Raudatin Sahly Fakultas Kedokteran, Universitas Mataram
Indah Eva Ajmala Fakultas Kedokteran, Universitas Mataram
Dewi Suryani Fakultas Kedokteran, Universitas Mataram

DOI: https://doi.org/10.29303/jk.v11i2.4689

Keywords: Vitamin D, Diabetes Mellitus Type 2, Insulin Resistance

Abstract

Vitamin D has a number of roles in various body systems with receptors scattered in many organs, showing a link between vitamin D and several chronic diseases such as cancer, diabetes and autoimmune disease. Several studies have shown the role of vitamin D in type 2 diabetes in controlling blood sugar levels and HbA1c levels. Vitamin D plays a role in increasing insulin sensitivity and secretion and suppressing inflammation in type 2 diabetes. Vitamin D has a protective role in various complications of type 2 diabetes, including diabetic nephropathy, diabetic neuropathy and diabetic retinopathy. Monitoring of vitamin D levels and vitamin D supplementation have a therapeutic role to controlling glycemic blood glucose and prevent complications in type 2.