Treatment Options for Patient with Unresectable Hepatocellular Carcinoma

Authors

  • Catarina Budyono Departemen of Internal Medicine, Faculty of Medicine, Mataram University
  • Ainun Fatiha DP Faculty of Medicine, Mataram, University
  • Baiq Aliza K.I. Faculty of Medicine, Mataram, University
  • I Gede Prabananda A. Faculty of Medicine, Mataram, University
  • Shafalyn Kalila R. Faculty of Medicine, Mataram, University

Keywords:

Hepatocellular Carcinoma, treatment

Abstract

Hepatocellular carcinoma (HCC) is a primary liver cancer that occurs due to the abnormal growth of hepatocytes. HCC is one of the cancers with the highest prevalence and incidence in the world. The main risk factors for HCC in Indonesia are chronic infection with hepatitis B virus, hepatitis C virus, and liver cirrhosis. The selection of the appropriate treatment modality for each patient is based on several patient-specific characteristics, such as tumor size, location, portal vein thrombosis, and liver function. Treatment options for unresectable hepatocellular carcinoma include intra-arterial therapy, multikinase inhibitors, and immunotherapy. Determining the stage is an important part of managing HCC because it can determine the treatment. One of the staging systems is the Barcelona Clinic Liver Cancer (BCLC) which categorizes HCC into 5 stages. Clinical severity criteria with BCLC stage are often used because they have good validity in predicting the prognosis of HCC patients.

Published

2021-12-31

Issue

Vol. 10 No. 4 (2021): Jurnal Kedokteran

Section

Articles

License

Authors who publish with Unram Medical Journal, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, websites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in University of Mataram's Journal of Medicine. 
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
  4. This journal is open access journal which means that all content is freely available without charge to users or / institution. Users are allowed to read, download, copy, distribute, print, search, or link to full text articles in this journal without asking prior permission from the publisher or author.