Analisis Faktor Risiko Kejadian Tumor Tiroid pada Klaster Keluarga di Daerah Pesisir Provinsi Nusa Tengga Barat

Abstract

Neoplasia is an uncontrolled growth of new tissue in the body, caused by uncontrolled gene mutations. One of the dominating endocrine neoplasia is thyroid neoplasia. Risk factors for thyroid tumors include age, place of residence, socioeconomics, and iodine intake. This study sampled families at risk of thyroid tumors at 6.1% who lived in the coastal province of West Nusa Tenggara (NTB) with an incidence rate of 0.85 per 100 population. This is an analytycal study with a cross-sectional design. Sample in this studied was using rule of thumb with a total sample of 50 people who fit the inclusion criteria. This research used the google form which contains a series of questionnaires and short interviews. Hypothesis testing using fisher test with probability value (p) <0.05 and logistic regression. Both iodine intake and age have association with the incidence of thyroid tumors, whereas Water Iodine Concentration (WIC) and socioeconomics have no association with p values respectively ​​0.038, 0.009, 0.126, and 0.129. The most influential risk factor was iodine intake with an OR/exp. B of 243,132,352.0. The probability value of each family member with a risk factors is 59% and without any  risk factors is 0%. The risk factors that influence the incidence of thyroid tumors in the family cluster in this study are iodine intake and age.