STRES OKSIDATIF YANG DIINDUKSI OLEH LATIHAN FISIK

Penulis

  • Ida Ayu Eka Widiastuti Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram

DOI:

https://doi.org/10.29303/jk.v11i4.4753

Kata Kunci:

Latihan fisik, stres oksidatif, produksi oksidan

Abstrak

Aktivitas dan latihan fisik yang teratur dapat membantu untuk tetap sehat. Namun demikian di sisi lain, latihan fisik sendiri berperan sebagai pemicu stres oksidatif. Jika pertahanan antioksidan kurang maka kerusakan dapat terjadi pada berbagai jaringan. Produksi oksidan yang berkaitan dengan latihan fisik dapat terjadi melalui beberapa jalur, yaitu: Kebocoran elektron dari rantai transfer elektron mitokondria, xanthine oxidase mengubah hypoxanthine menjadi asam urat, namun dengan menggunakan oksigen sebagai akseptor elektron untuk membentuk superoksida selama reperfusi, produksi radikal bebas oleh NADPH oxidase, pembentukan superoksida pada mitokondria otot akibat peningkatan temperatur dan autooksidasi oksihemoglobin menjadi methemoglobin, menyebabkan produksi superoksida.

Unduhan

Diterbitkan

2022-12-30

Terbitan

Vol 11 No 4 (2022): Jurnal Kedokteran

Bagian

Articles

Lisensi

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