Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan Nacetylcysteine

Authors

  • Mia Putri Sahara Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram
  • Siska Julia Cindy Winangsih Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram
  • Siti Jaisy Millah Hadaina Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram
  • Komang Pranayoga Prandhana Putra Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram
  • Rizqi Al Kasiron Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram
  • Catarina Budyono Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram

DOI:

https://doi.org/10.29303/jk.v11i4.4750

Keywords:

N-acetylcysteine, Non-Acetaminophen Induced Acute Liver Failure

Abstract

Gagal hati akut merupakan suatu kondisi dimana terjadi disfungsi hati yang bersifat akut. Terdapat dua jenis dari gagal hati akut ini yaitu acetaminophen induced acute liver failure dan non acetaminophen induced acute liver failure.Gagal hati akut memiliki penilaian angka insidensi sebanyak 1-6 kasus per 1 juta orang setiap tahunnya pada berbagai negara maju, sedangkan untuk Negara berkembang penilaian angka insidensi diperkiraan lebih besar karena memiliki angka insidensi hepatitis yang tinggi, di Amerika, diperkirakan sebanyak 2500 kasus gagal hati akut per tahunnya. Sampai saat ini, tidak ada pengobatan yang mampu untuk nonacetaminophen-incuded acute liver failure selain dengan cara transplantasi hati. Berdasarkan hasil analisis penelitian yang dilakukan, terapi pengobatan Nacetylcysteine (NAC) pada non-acetaminopen-induced acute liver failure dapat menjanjikan. Non-acetaminophen induced acute liver failure dengan meningkatkan hemodinamik sistemik dan penghantaran oksigen ke jaringan.

Downloads

Published

2022-12-30

Issue

Vol. 11 No. 4 (2022): Jurnal Kedokteran

Section

Articles

License

Authors who publish with Unram Medical Journal, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, websites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in University of Mataram's Journal of Medicine. 
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
  4. This journal is open access journal which means that all content is freely available without charge to users or / institution. Users are allowed to read, download, copy, distribute, print, search, or link to full text articles in this journal without asking prior permission from the publisher or author.