Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan Nacetylcysteine
DOI:
https://doi.org/10.29303/jk.v11i4.4750Keywords:
N-acetylcysteine, Non-Acetaminophen Induced Acute Liver FailureAbstract
Gagal hati akut merupakan suatu kondisi dimana terjadi disfungsi hati yang bersifat akut. Terdapat dua jenis dari gagal hati akut ini yaitu acetaminophen induced acute liver failure dan non acetaminophen induced acute liver failure.Gagal hati akut memiliki penilaian angka insidensi sebanyak 1-6 kasus per 1 juta orang setiap tahunnya pada berbagai negara maju, sedangkan untuk Negara berkembang penilaian angka insidensi diperkiraan lebih besar karena memiliki angka insidensi hepatitis yang tinggi, di Amerika, diperkirakan sebanyak 2500 kasus gagal hati akut per tahunnya. Sampai saat ini, tidak ada pengobatan yang mampu untuk nonacetaminophen-incuded acute liver failure selain dengan cara transplantasi hati. Berdasarkan hasil analisis penelitian yang dilakukan, terapi pengobatan Nacetylcysteine (NAC) pada non-acetaminopen-induced acute liver failure dapat menjanjikan. Non-acetaminophen induced acute liver failure dengan meningkatkan hemodinamik sistemik dan penghantaran oksigen ke jaringan.Downloads
Published
2022-12-30
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