Aspek Patofisiologi Meningitis Tuberkulosis dan Tuberkuloma

Authors

  • Putu Wika Pramesti Iswari Mahasiswa Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia
  • Ni Putu Visty Widhiani Mahasiswa Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia
  • Shalsa Damai Akelba Mahasiswa Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia
  • Tri Sastra Pradhini Mahasiswa Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia
  • Herpan Syafii Harahap Staff Pengajar Departemen Neurologi Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia.
  • Stephanie Elizabeth Gunawan Staff Pengajar Departemen Neurologi Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia.
  • Safat Wahyudi Staff Pengajar Departemen Neurologi Program Studi Pendidikan Dokter, Fakultas Kedokteran Universitas Mataram, Indonesia.

DOI:

https://doi.org/10.29303/jk.v12i3.4448

Keywords:

Pathophysiology, Tuberculosis, Meningitis

Abstract

Tuberkulosis (TB) hingga saat ini masih menjadi masalah kesehatan di dunia. Tuberkulosis merupakan penyakit infeksius dengan tingkat mortalitas yang tinggi meskipun untuk penyebarannya dapat dicegah. TB dapat menimbulkan komplikasi lain salah satunya adalah meningitis TB. Mekanisme penyebaran bakteri TB melalui pembuluh darah ke organ lain dipengaruhi oleh sistem imun. Bakteri TB menggunakan mekanisme “trojan horse†untuk masuk ke blood brain barrier (BBB). Pada sistem saraf pusat, terdapat aktivitas imun yang akan melawan bakteri TB dan membentuk tuberkuloma atau rich foci. Apabila rich foci ini ruptur, bakteri TB akan dilepaskan ke ruang subarachnoid atau sistem ventrikel menyebabkan terjadinya meningitis TB.   

Downloads

Published

2023-09-30

Issue

Vol. 12 No. 3 (2023): Jurnal Kedokteran

Section

Articles

License

Authors who publish with Unram Medical Journal, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, websites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in University of Mataram's Journal of Medicine. 
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
  4. This journal is open access journal which means that all content is freely available without charge to users or / institution. Users are allowed to read, download, copy, distribute, print, search, or link to full text articles in this journal without asking prior permission from the publisher or author.